Reading � Hunger 2 misc

Greg Detre

Thursday, 01 June, 2000

Where/who?

Obesity

1. Endocrine factors, e.g. hyperinulinemia (rare)

2. Externality � Schachter: obese people may be more reactive to the sensory properties of food

3. Palatability � enhanced palatabilty in human diet, leading to imbalance between orosensory control signals and gastrointestingal and post-absorptive satiety signals

4. Variety � enhacned variety in human diet, which leads to increased food intake because satiety is partly sensory-specific

5. Meal pattern

inter-meal interval is normally regulated

obese tend to eat late in the day

6. Meal concentration � tends to be high in the obese, and only partial compensation is possible

7. Stress-induced eating

8. Regulation to internal signals is poor, e.g. 2 weeks to adjust to altered caloric composition of the diet

9. Brown Adipose tissue

important in thermo-regulation in rats

can be triggered by variety-induced eatin gin rats

little BAT in human, although metabolism does normally partially compensate for altered energy intake